Role of prostaglandins, nitric oxide and potassium channel in the blunting of hypoxic pulmonary vasoconstriction in the high altitude adaptive animal / 中国病理生理杂志
Chinese Journal of Pathophysiology
;
(12)1989.
Artigo
em Chinês
| WPRIM
| ID: wpr-522631
ABSTRACT
AIM:
To investigate the possible role of prostaglandin, NO and potassium channel in the adaptive blunting of hypoxic pulmonary vasoconstriction (HPV) in the high altitude animal (pika).METHODS:
The effect of L-NAME, indomethacin and 4-AP on the response of isolated lung strips of pika and Wistar rats instead of pulmonary artery to acute hypoxia were studied.RESULTS:
(1) After inhibition of prostaglandins by indomethacin, the percentage increase in hypoxic constriction in lung tissue strip of pikas was greater than that in Wistar rats[(64.7?50.9)% vs (19.7?14.1)%], P
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Pathophysiology
Ano de publicação:
1989
Tipo de documento:
Artigo
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