Evaluation of N-Terminal Pro Brain Natriuretic Peptide for Assessment of Left Ventricular Remodeling and Left Ventricular Function in Acute Myocardial Infarction / 中国循环杂志

ABSTRACT

Objective:To evaluate the value of N terminal pro brain natriuretic peptide(NT proBNP) in assessment of left ventricular remodeling and left ventricular function in patients with acute myocardial infarction. Methods:Echocardiography was performed in 61 patients with acute myocardial infarction(AMI) and in 20 control participants Plasma samples for NT proBNP were obtained at 48 96 hours after AMI.NT proBNP was determined by ELISA method. Results:Compared with controls NT proBNP in AMI patients were significantly higher ( p 55.The sensitivity,specificity and accuracy were 84 6%,65 5% and 77 7%,respectively.In Multivariate analysis NT proBNP was correlated with Killip classification and wall motion index. Conclusion:Plasma NT proBNP was significantly increased in AMI patients Plasma NT proBNP was correlated with cardiac functional class and extension of myocardial infraction.