Study on Quality Control of Guanxinshu Tablets / 中国药房

ABSTRACT

OBJECTIVE:To develop a method to control the quality of Guanxinshu tablets by HPLC.METHODS:Using HPLC as the determination method,the separation was performed on C 18 column(150mm?4.6mm,5?m)with a mobile phase of MeOH∶0.1%H 3 PO 4 (1∶2).The detective wavelength was320nm.RESULTS:The calibration curve was linear(r=0.9994)within the range of1.2～48?g/ml for ferulic acid and the average recovery was101.00%,RSD=4.56%(n=6).CONCLUSI_ ONThe method is simple and quick and it is suitable for the quality control of Guanxinshu tablets.