Experiment of the Photostability of the Levofloxacin Hydrochloride Injection / 中国药房

ABSTRACT

OBJECTIVE: To study the photostability of the levofloxacin hydrochloride injection. METHODS: The content of levofloxacin hydrochloride was determined and its UV spectra changes were observed after being lighted by three different light sources-the UV light, the sunlight and the natural light for different periods of time. Whether there is any decomposed product or not was determined by TLC. RESULTS: There were decompositions of levofloxacin hydrochloride injection subjected to illumination from three light resources, with that under the sunlight decomposed faster; Rf value under TLC of the decomposed product was found to be 0.72. CONCLUSION: Levofloxacin hydrochloride injection should be kept away from UV light, the sunlight and the natural light.