Observation of the Therapeutic Effect of Compound Glycyrrhizin on Portal Hypertension Patients during the Perioperative Period / 中国药房

ABSTRACT

OBJECTIVE:To observe the clinical therapeutic effect of compound glycyrrhizin on portal hypertension pa-tients between and after the operative period.METHODS:Apart from a general treatment,13patients with portal hypertension and the complication of the alimentary tract hemorrhage were also administered by drip phleboclysis with60ml to80ml of compound glycyrrhizin injection,which were added to250ml glucose injection at a concentration of5%,once a day for5to10days before the operation and continue for1to2weeks after the operation.RESULTS:The preoperative symptoms,signs and liver function showed a significant improvement;no significant changes were found in the liver function after operation,the incidence of the ascites lowered and the degree of the ascites lowered too,which had a significant difference compared with the control group(P