Preparation Technique of Fluconazole for Injection and Its Stability Study / 中国药房
China Pharmacy
;
(12)2001.
Artigo
em Chinês
| WPRIM
| ID: wpr-524972
ABSTRACT
OBJECTIVE:
To select a technique for preparation of fluconazole for injection and to establish a method for determination of its content.METHODS:
The formula was selected on the basis of pH value and species of solution adjuvant.The content was determined by HPLC.RESULTS:
The preparation was stable when pH value was between6.5~8.5,and its clarity could be increased by propylene glycol.The detectable concentration of fluconazole showed a good linear correlation in the range of40~200?g/ml.The average recovery was100.37%,RSD=1.37%(n=3).CONCLUSION:
The fluconazole for injection prepared by the present technique is stable in quality and the method for content determination is accurate and practicable.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
China Pharmacy
Ano de publicação:
2001
Tipo de documento:
Artigo
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