Effect of Huoxiangzhengqi Liquid on Substance P of Rats / 中国药房

ABSTRACT

OBJECTIVE:To observe the effect of huoxiangzhengqi liquid on substance P(SP)of rats.METHODS:The rats were randomly divided into trial group(huoxiangzhengqi liquid)and control group(normal saline),the gastrointestinal motility of rats were observed1hour and6hours after drenched with the corresponding drugs,levels of SP in serum,sinus ventriculi,jejunum tissues homogenate and the distributions of SP positive products in sinus ventriculi and jejunum tissues of2groups of rats were also determined.RESULTS:The gastrointestinal motility of the trial group was markedly enhanced after medication,particularly1hour after medication;Compared with the control group,levels of SP in serum,sinus ventriculi,jejunum tissues homogenate and SP positive products in sinus ventriculi,jejunum tissues had a significant increase in the trial group(P