Cost-effectiveness Analysis on Fluoxetine and Paroxetine in the Treatment of Depressive Disorder by Evidence-based Medicine Method / 中国药房

ABSTRACT

OBJECTIVE:To evaluate the cost-effectiveness of fluxetine and paroxetine in the treatment of depressive disorders.METHODS:The clinical data of fluxetine and paroxetine in the treatment of depressive disorders were collected by evidence-based medicine method and which were evaluated by cost-effectiveness analysis in pharmacoeconomics.RESULTS:The cure rates of fluxetine and paroxetine in the treatment of depressive disorders were36.30%and58.73%,respectively,and the cost-effectiveness ratios of which were14.13and9.73,respectively.The incremental cost-effectiveness ratio of the latter vs.the former was2.60.CONCLUSION:The cost-effectiveness of paroxetine is superior to fluxetine in the treatment of depressive disorders.