Drug-resistance Monitoring and Medication Analysis:Survey of 148 Pseudomonas Aeruginosa Infection Cases / 中国药房

ABSTRACT

OBJECTIVE:To probe into the status quo of the drug resistance and the medication of pseudomonas aeruginosa so as to provide references for the clinic in the controlling of pseudomonas aeruginosa infection.METHODS:The susceptive rates of the susceptibility test performed on 148 pseudomonas areuginosa infection cases confirmed in 2004 in our hospital were collected statistically and a whole range tracking statistics were conducted on the use of antibacterials.RESULTS:Pseudomonas aeruginosa had a strong drug resistance,which had a different degree of drug resistance to all antibacterials;Antibiotics like piperacillin/tazobactam,ceftazidime and carbopenem took the lead in terms of their susceptive rates,which stood at 75.68%,73.65%and 70.27%,respectively;The cross resistances of the third generation cephalosporins and the compound agents of the third generation cephalosporins and their enzyme inhibitor were serious and which kept increasing rapidly;The adoption rates for the susceptive kinds were less than 50%before the susceptibility test.CONCLUSION:An effective way to control pseudomonas aeruginosa infection is to conduct strain culture and isolation and perform susceptibility test as early as possible.