Effect of oxymatrine on sodium channel in isolated ventricular myocytes in guinea pig / 中国病理生理杂志
Chinese Journal of Pathophysiology
;
(12)2000.
Artigo
em Chinês
| WPRIM
| ID: wpr-525949
ABSTRACT
AIM:
To observe the effect of oxymatrine on sodium channel in isolated cardiomyocytes of guinea pig.METHODS:
Single ventricular myocytes of guinea pigs were obtained by enzymatic dissociation. The whole - cell patch clamp recording technique was used to record the change of sodium current by different dosage of oxymatrine from 1 to 1 000 ?mol?L-1 .RESULTS:
Oxymatrine decreased sodium current in a dose - dependent manner. Oxymatrine (100 ?mol?L-1) decreased the current density by 40% (P
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Pathophysiology
Ano de publicação:
2000
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS