Quality Study on Guanxin Ⅱ Decoction / 中国药房

ABSTRACT

OBJECTIVE:To investigate the variation degrees of the active components in the same batch No.GuanxinⅡdecoctions under the same decoction technics.METHODS:Crude drug of the same batch No.of the same formula was decocted,every decoction detail was tried to be kept under control,the contents of the active components in 5 batches of GuanxinⅡdecoctions were determined and the mean value of which was calculated as well.RESULTS:In terms of the contents of crude drugs,those of tanshinol,protocatechualdehyde,peoniflorin and ferulic acid were respectively(0.773?0.0 656)mg/g,(36.591?3.0 590)?g/g,(2.655?0.2 454)mg/g,(85.052?7.5 469)?g/g.CONCLUSION:Referenced by the criterion that the content variation coefficient among different batches of decoctions should be less than 10%,the contents of active components in each decoction were all up to the standards.Referenced by the criterion that there should be no statistical difference among different batches of decoctions,more influential factors on the active components of decoctions should be brought into consideration in the quality control.