Extension and Application of the Commonly-used Pharmacokinetic Formula / 中国药房

ABSTRACT

OBJECTIVE:To direct rational use of drugs in the clinic by applying pharmacokinetic theory.METHODS:A new formula practicable for clinic was derived by expanding and transforming the basic pharmacokinetic formula.A practical pharmacokinetic parameter table was established and from which the pharmacokinetic parameters needed by clinic were avail?able.RESULTS:With the help of practical pharmacokinetic parameter table,the rationality of clinical medication can be in?vestigated at any time.Combined with monitoring of blood concentration,personalized medicine can be realized.CONCLU?SION:The practical pharmacokinetic parameter table is an important tool in directing personalized medicine.