A Case of Large Cell Lung Carcinoma with Rhabdoid Phenotype Presenting as Cutaneous Metastasis / 대한피부과학회지
Korean Journal of Dermatology
;
: 269-273, 2014.
Artigo
em Coreano
| WPRIM
| ID: wpr-52762
ABSTRACT
Large cell carcinoma with a rhabdoid phenotype is very rare. We report the case of a 53-year-old man who presented with multiple nodules on the scalp, face, and trunk. A skin biopsy revealed large cell carcinoma with a rhabdoid phenotype throughout the dermis. Tumor cells had abundant cytoplasm, eccentric nuclei, and prominent nucleoli and did not adhere to each other. Immunohistochemical tests showed positive reactions for vimentin, epithelial membrane antigen (EMA), and thyroid transcription factor-1 (TTF-1) and weakly focal reactions for pan-CK, CK7, and p63. Imaging studies and a percutaneous lung biopsy were performed and the results were consistent with a large cell lung carcinoma with a rhabdoid phenotype. Based on these clinical and histopathological findings, we concluded that his condition was a cutaneous metastasis from a large cell lung carcinoma with a rhabdoid phenotype, which occurs very rarely.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fenótipo
/
Couro Cabeludo
/
Pele
/
Glândula Tireoide
/
Vimentina
/
Biópsia
/
Tumor Rabdoide
/
Carcinoma de Células Grandes
/
Mucina-1
/
Derme
Limite:
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Dermatology
Ano de publicação:
2014
Tipo de documento:
Artigo
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