Three Cases of Generalized Granuloma Annulare in Infancy Following Bacillus Calmette-Guerin Vaccination / 대한피부과학회지

ABSTRACT

Generalized granuloma annulare is a rare benign granulomatous dermatosis characterized by disseminated necrobiotic dermal papules forming an annular or nonannular configuration. It usually occurs in adults and rarely affects infants. Histologically, it presents as a lymphohistiocytic granuloma associated with varying degrees of connective tissue degeneration. Clinical associations between generalized granuloma annulare and diabetes mellitus, thyroid disease, malignancy, infection, and vaccination have been reported. There are a few cases reports of generalized granuloma annulare associated with Bacillus Calmette-Guerin (BCG) vaccination. Herein, we report three cases of generalized granuloma annulare following BCG vaccination in infants.