The Relationship of Serum Levels of Adiponectin and Tumor Necrosis Factor-? in the First-degree Family Relatives of Patients with Type 2 Diabetic / 中国慢性病预防与控制
Chinese Journal of Prevention and Control of Chronic Diseases
;
(6)2006.
Artigo
em Chinês
| WPRIM
| ID: wpr-528181
ABSTRACT
Objective To study the changes of serum levels of adiponectin and tumor necrosis factor-?in the first-degree family relatives of patients with type 2 diabetic mellitus and the relationship of adiponectin and TNF-?with insulin resistance.Methods 45 families with type 2 diabetes were recruited.The observation group comprised 83 first-degree relatives who were with normal glucose tolerance(NGT).The normal control group comprised 76 NGT spouses of the probands and his/her siblings.The levels of fasting blood glucose,insulin,proinsulin,lipid,adiponectin and TNF-? were measured among two groups.Insulin resistance was calculated using the homeostasis assessment(HOMA).Results The levels of TG,fasting insulin(FINS),fasting proinsulin(FPI),TNF-? and HOMA-IR in first-degree relatives were significantly higher(P
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Prevention and Control of Chronic Diseases
Ano de publicação:
2006
Tipo de documento:
Artigo
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