Determination of L-Arginine Content in Cefradine for Injection by HPLC / 中国药房
China Pharmacy
;
(12)1991.
Artigo
em Chinês
| WPRIM
| ID: wpr-529862
ABSTRACT
OBJECTIVE:
To establish an HPLC method for the determination of the content of L-arginine in cefradine for injection.METHODS:
The chromatographic analysis was carried on LiChrospher Diol column,and the mobile phase was composed of 0.01 mol?L-1 ammonium dihydrogen phosphate buffer solution(adjusted pH to 2.0?0.1 with phosphoric acid)-acetonitrile(25∶75)at a flow rate of 1.0 mL?min-1;the column temperature was 30 ℃;the detection wavelength was 206 nm,and the sample size was 20 ?L.RESULTS:
The linear range of L-arginine was 51.2~307.2 ?g?mL-1(r=0.999 9).The average recovery was 100.7%(RSD=0.6%).CONCLUSION:
The method is rapid,accurate and simple,and suitable for the determination of L-arginine in cefradine for injection.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
China Pharmacy
Ano de publicação:
1991
Tipo de documento:
Artigo
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