Determination of Dissolution of Warfarin Potassium Tablets by UV Spectrophotometry / 中国药房
China Pharmacy
;
(12)2005.
Artigo
em Chinês
| WPRIM
| ID: wpr-530466
ABSTRACT
OBJECTIVE:
To establish a method for the determination of dissolution of warfarin potassium tablets.METHODS:
The dissolution of warfarin potassium tablets was determined by UV spectrophotometry at a detection wavelength of 283 nm with 0.1 mol?L-1 hydrochloric acid as the solvent at a volume of 900 mL. The rotation speed was 50 r?min-1 and the sampling time was 30 min.RESULTS:
The method showed a good linear relationship in the range of 5~30 ?g?mL-1(r=0.999 9). The average recovery was 100.53%(RSD=0.69%). The dissolutions of 3 batches of samples were all above 90%.CONCLUSION:
The method is simple,accurate and reliable,and it can be applied for the determination the dissolution of warfarin potassium tablets.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
China Pharmacy
Ano de publicação:
2005
Tipo de documento:
Artigo
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