Compatible Stability of Gatifloxacin for Injection in Combination with Cefathiamidine for Injection / 中国药房

ABSTRACT

OBJECTIVE: To study the compatible stability of gatifloxacin for injection in combination with cefathiamidine for injection in 0.9% sodium chloride injection or in 5% glucose injection.METHODS: Changes in appearance and pH value of the mixture of gatifloxcation and cefathiamidine within 8 hours after mixing were respectively observed and determined under room temperature(20?1)℃,and the contents were determined by dual ultraviolet spectrophotometry.RESULTS: The appearance,pH value and contents as well as the ultraviolet absorption peak shape of the mixture showed no significant change within 8 hours after mixing in 0.9% sodium chloride injection or 5% glucose injection.CONCLUSION: Gatifloxacin for injection can be mixed with cefathiamidine for injection in 0.9% sodium chloride injection or 5% glucose injection to use.