Content Determination of Chlorhexidine Acetate in Daobian Suppository by RP-HPLC / 中国药房
China Pharmacy
;
(12)2001.
Artigo
em Chinês
| WPRIM
| ID: wpr-532084
ABSTRACT
OBJECTIVE:
To establish a RP-HPLC method for the determination of the content of chlorhexidine acetate in daobian suppository.METHODS:
The determination was performed on Diamonsil C_(18)column,The mobile phase consisted of acetonitrile-water-triethylamine(30700.5,with pH adjusted to 3.0 by phosphoric acid)at a flow rate of 1.0 mL?min~(-1),The detective wavelength was 260 nm,the sample size was 20?L and the column temperature was maintained at 30℃.RESULTS:
The linear range of Chlorhexidine Acetate was 1.092~13.10?g?mL~(-1)(r=0.999 9)and its average recovery was 98.29%(RSD=2.16%,n=9).CONCLUSIONS:
The method is simple and accurate,and it can be used for the determination of the content of chlorhexidine acetate in daobian suppository.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
China Pharmacy
Ano de publicação:
2001
Tipo de documento:
Artigo
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