Content Determination of Preservative Ethylparaben in Hospital Preparation / 中国药房
China Pharmacy
;
(12)2005.
Artigo
em Chinês
| WPRIM
| ID: wpr-532231
ABSTRACT
OBJECTIVE:
To establish a RP-HPLC method for the determination of preservative ethylparaben content in hospital preparation.METHODS:
The determination was carried out on Spherisorb C18 column and the mobile phase consisted of acetonitrile-water(50∶50,V/V) at a flow rate of 1 mL?min-1.The column temperature was set at 35 ℃;the detection wavelength was set at 254 nm and the sample size was 20 ?L.RESULTS:
The linear range of ethylparaben was 1.812 5~18.125 0 ?g?mL-1(r=0.999 9) with an average recovery rate of 99.92%.The intra-day RSD was less than 2.10% and inter-day RSD was less than 4.89%.CONCLUSION:
The method is simple,rapid and accurate,and applicable for the determination of ethylparaben content in hospital preparation.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
China Pharmacy
Ano de publicação:
2005
Tipo de documento:
Artigo
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