Pharmacodynamics of Miniaoning Granules / 中国药房

ABSTRACT

OBJECTIVE:To observe the anti-inflammatory,diuretic,and antipyretic action of Miniaoning granules after improvement of its preparation technology.METHODS:The rats' feet swelling degree and the mice's ear swelling degree,the urine volume,and the body temperature action of Miniaoning granules in vitro were observed through rats' feet swelling method,dimethyl benzene-induced mice ear swelling method,diuretic experiment,yeast-induced rats' febrile,respectively.RESULTS:After medication,the degree of rats' feet swelling and mice's ear swelling were significantly attenuated,and the urine volume increased markedly and body temperature lowered.CONCLUSION:As compared with the original formulations,Miniaoning granules prepared in improved technology have similar antipyretic effect but more potent anti-inflammatory and.diuretic action.