Expression and Clinical Significance of Serum Soluble Epithelial Cadherin in Patients with Gastric Cancer / 中国药房

ABSTRACT

OBJECTIVE: To study the correlation between serum soluble epithelial cadherin(sE-Cd) of patients with gastric carcinoma(GA) and the invasion and recurrence of gastric cancer.METHODS: Concentrations of soluble E-cadherin in 20 healthy adults,20 recurrent cases after GA surgery and 80 GA cases at 0,7 and 14 days after operation were determined by enzyme linked immunosorbent assay so as to explore the regular pattern;the correlation between sE-Cd level and the pathology and clinical features of GA was analyzed,and the carcinoembryonic antigen(CEA) and CA19-9 which served as controls were detected.RESULTS: Serum concentrations of sE-Cd were higher in the patients with postoperative relapse of gastric carcinoma than in normal control(P