Titer Determination of Main Component in Kitasamycin Tablets and Acetylkitasamycin Dry Suspension by Turbidimetry / 中国药房
China Pharmacy
;
(12)2007.
Artigo
em Chinês
| WPRIM
| ID: wpr-533063
ABSTRACT
OBJECTIVE:
To determine the titer of main component in kitasamycin tablets and acetylkitasamycin dry suspension.METHODS:
Staphylococcus aureus was used as test organism and which were cultured at (37?0.5) ℃ for about 4~5 hours by adding 1.0%~1.5% kitasamycin and 2.0%~2.5% acetylkitasamycin,then the absorbance was determined at a wavelength of 530 nm.RESULTS:
The linear range of kitasamycin was 0.5~4.0 IU?mL-1 and that of acetylkitasamycin was 0.45~6.3 IU?mL-1,and their recovery rates were 101.7%(RSD=1.9%,n=9) and 101.1%(RSD=2.1%,n=9),respectively.CONCLUSION:
The established turbidimetry is sensitive,rapid yet with few influencing factors,thus it is applicable for the titer determination of main component in kitasamycin tablets and acetylkitasamycin dry suspension.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
China Pharmacy
Ano de publicação:
2007
Tipo de documento:
Artigo
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