Methotrexate (MTX) in medical treatment of unruptured ectopic pregnancies: a non-controlled clinical trial at Hung Vuong hospital

ABSTRACT

110 cases of unruptured ectopic pregnancy were treated, among them 61 cases (55,5%) with 1 dose of methotrexate, 40 with 2 doses (36,4) and 9 with 3 doses (8,1%). Successful rate reached 90,9% (84-95%). β- HCG took 13 (±10,3) days to return to negative point. It took 31,8 (±20,7) days for ectopic pregnant mass to disappear. Not any severe side effect was notified, except 5 cases of nausea. After treating and 12 months of follow up,47,8% of cases had got new pregnancy, among them,9,9% had reccured ectopic pregnancy. Methotrexat is an efficacious internal therapeutic for unrupted ectopic pregnancy