Composition of Clinically Isolated Gram-negative Bacilli and Drug Resistance in Our Hospital from 2001～2008 / 中国药房

ABSTRACT

OBJECTIVE:To provide clinicians with reliable basis about rational use of antibacterials. METHODS:The gram-negative bacilli isolated clinically in our hospital from 2001 to 2008 and their drug resistance were analyzed retrospectively. RESULTS:A total of 14 428 strains of pathogenic bacteria were isolated from 2001 to 2008,of which,9 391 strains (65.1%) were gram-negative bacilli,leading the list were Escherichia coli,Pseudomonas aeruginosa,Enterobacter cloacae,Klebsiella pneumoniae and Acinetobacter,and the detected rate of Acinetobacter baumannii increased year by year. Gram-negative bacilli were resistant to commonly used antibacterials more or less,with their resistance rates to ampicillin on the high side,but their resistance rates to imipenem,pipercillin/tazobactam and amikacin were low. CONCLUSION:The composition of clinically isolated Gram-negative bacilli and their drug resistance patterns were always in a change,therefore,clinicians should familiarize with this change as well as the change of drug resistance and improve their level of rational use of antibiotics.