Efficacy and Safety of Wenxin Granules in the Treatment of Congestive Heart Failure: A Systematic Review / 中国药房

ABSTRACT

OBJECTIVE:To evaluate the efficacy and safety of Wenxin granules for congestive heart failure (CHF).METHODS:Literatures about random controlled trails of Wenxin granules for CHF were retrieved from PubMed,EMbase,Cochrane,CBMdisc,CNKI while other relative research papers were searched by hands.Included studies were evaluated by methodological quality assessment and analyzed using RevMan5.0.0 software.RESULTS: Eight randomized controlled trials of Wenxin granules were included.The results of Meta-analysis showed the obvious effective rate and effective rate of improvement of heart function in patients with CHF or CHF complicated by ventricular arrhythmia (VA) in study group were better than in control group.The differences between study group and control group had no statistical significance.The obvious effective rate of improvement of VA and the levels of NSVT,PVBs and LVEF in patients with CHF complicated by VA in study group were superior to control group.The differences between study group and control group had statistical significance(P