Effect of Irbesartan and Losartan on Pharmacokinetics of Cyclosporin A in Rabbits / 中国药房
China Pharmacy
;
(12)2001.
Artigo
em Chinês
| WPRIM
| ID: wpr-533627
ABSTRACT
OBJECTIVE:
To study the effect of irbesartan and losartan on pharmacokinetics of cyclosporin A(CsA)in rabbits.METHODS:
12 rabbits were randomly divided into two groups(n=6). In self-controlled study,plasma concentration of CsA in rabbits of two groups before and after treating with combination of irbesartan and losartan were determined and pharmacokinetics parameters were examined.RESULTS:
After combination of irbesartan or losartan,the Cmax and AUC0~24 of CsA were significantly increased(P
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
China Pharmacy
Ano de publicação:
2001
Tipo de documento:
Artigo
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