Establishment of Database and Study on Epidemiological Characteristics of ADR Caused by Shenmai Injection / 中国药房

ABSTRACT

OBJECTIVE:To investigate the epidemiological characteristics of adverse reaction(ADR) caused by Shenmai injection.METHODS:By retrieving from Chinese medical periodicals issued in 1990 to 2010,145 cases of ADR induced by Shenmai injection were collected to establish database using ACCESS.Based on established database,the epidemiological information was analyzed statistically.RESULTS:The incidence of ADR was the highest in the middle-aged and old sufferers(87.6%),and was 37.9% in the male(n=55) and 62.1% in the female(n=90).Of primary diseases cases,cardiovascular disease took up 62.1%.The incidence of allergic reaction took up 38.0% in ADR cases and ADRs usually occurred within 30 min after first injection(64.8%).CONCLUSION:The establishment of ADR database is beneficial to the storage and analysis of ADR information and provided reference for the prevention and therapy of ADR caused by Shenmai injection.