Clinical Efficacy of Strengthening Spleen,Reducing Phlegm and Stasis-dispelling Recipe Combined with Atorvastatin Calcium Tablet for Hyperlipidemia of Phlegm-turbidity Accumualtion / 中国药房

ABSTRACT

OBJECTIVE:To observe the clinical efficacy of strengthening spleen,reducing phlegm and stasis-dispelling recipe combined with atorvastatin calcium tablet for hyperlipidemia of phlegm-turbidity accumualtion.METHODS:In prospective study,80 patients with hyperlipidemia of phlegm-turbidity accumulation received traditional Chinese medicine combine with atorvastatin calcium tablet(therapy group) or atorvastatin calcium tablet alone(control group) with each group of 40 cases.Both groups were given oral dose of atorvastatin calcium tablet 10 mg before supper for 8 weeks.Therapy group were additionally given strengthening spleen,reducing phlegm and stasis-dispelling recipe.The levels of serum,TC,TG,HDL-C,LDL-C were observed.RESULTS:Total response rate of therapy group was 92.5%,which was better than control group of 85%.The improvements of TC,TG,LDL-C and HDL-C in therapy group were superior to control group.The improvement of clinical symptom in therapy group was better than control group according to the score of dizziness,sleepiness,chest tightness and palpitation,abdominal distention.Adverse drug reaction had not observed in both groups.CONCLUSION:Traditional Chinese medicine combine with atorvastatin calcium tablet has better effect than atorvastatin calcium tablet alone.2 groups show similar safety of drug use.