Systematic Review on Omeprazole and Ranitidine in the Treatment of Peptic Ulcer / 中国药房

ABSTRACT

OBJECTIVE:To evaluate clinical efficacy and ADR of omeprazole and ranitidine in the treatment of peptic ulcer.METHODS:Literatures were retrieved from China scientific journal database and Wanfang database.Meta-analysis was conducted using Revan 5.0 software.Fixed effect model was used to combined information and non-heterogeneity.The cause of heterogeneity was also analyzed.Sensitivity analysis and subgroup analysis were used to dispose the heterogeneity.Random effect model was used for analysis if the heterogeneity cannot be eliminated.RESULTS:Total effective rate of omeprazole for peptic ulcer was significantly different from ranitidine [P