Utilization of Psychotropic Drugs in Hospitalized Patients with Depression of Our Hospital in 2008 / 中国药房

ABSTRACT

OBJECTIVE:To investigate the drug treatment of hospitalized patients with depression in our hospital during 2008. METHODS: In cross section study, the medical records which in accordance with ICD-10 diagnostic criteria for depression disorders in our hospital during 2008 were retrieved, then the utilization of psychotropic drugs was analyzed and summarized. RESULTS: The utilization rate of new antidepressants including selective serotonin reuptake inhibiter (SSRI), selective serotonin and noradrenaline reuptake inhibiter (SNRI), noradrenaline and specific serotonin antagon (NaSSA) reached 89.9%, among which sertraline accounted for the largest proportion (22.5%). New antidepressants combined with atypical antipsychotics took up a big proportion, particularly quetiapine (39.2%). CONCLUSION: New antidepressants become the mainstream drug in the treatment of depression. Drug combination occupies a big proportion, especially combining with atypical antipsychotics. The safety of drug combination need to be further explored.