Effects of Rabeprazole on Symptoms and Psychological Status in Patients with Non-erosive Reflux Disease / 中国药房

ABSTRACT

OBJECTIVE:To investigate the effect of rabeprazole on symptoms and psychological status of patients with non-erosive reflux disease (NERD).METHODS:GerdQ questionnaire survey was performed in 169 patients who accorded with diagnosis criteria to investigate relevant symptoms of gastroesophageal reflux disease in 1 week.Symptoms scores were carried out according to the occurrence frequency of heartburn,gastroesophageal reflux,nausea and epigastric pain,etc.RESULTS:159 NERD patients completed 4 weeks of treatment.GerdQ score was (10.44?1.62) and SAS score (47.11?10.92),SDS score (44.59?11.2) before treatment.After 1 week of treatment,relevant clinical symptoms relieved obviously,and SAS score and SDS score were lower than before treatment strikingly.The decrease of SAS score and SDS score were more significant after 4 weeks of treatment.There were statistical significance (P