Effects of Gwe (an active ingridient derived from Chinese herb)on immunological responses / 中国免疫学杂志

ABSTRACT

Gwe, an active ingridient derived from Chinese herb, possess profound effects on immune functions in mice in vivo and human peripheral lymphocytes (PBL)in vitro. The mitogenesis stim ulated with ConA or LPS, LAK cytotoxicity, spontaneous proliferation of thymocytes and prodution of IL-2 may all be increased markedly after treatment with Gwe in mice, but the CIC (circulating immune complexes) in sera decreased conpared to saline controls. The results shows that GWe influence preferentially on T-cell in a dose-dependent manner.