Repairing Function of Embryonic Spinal Cord on the Defect Tissue after Acute Spinal Cord Injury in Adult Rats / 中华创伤杂志

ABSTRACT

Using microsurgery techniques, we transplanted a piece of embryonic spinal cord (E_(14)) into spinal cord of adult rats that were hemisectly injured, with a small cavity left in it. The results were observed at days 7, 15. 30, 60, 120 and 240 after operation. The findings showed that 74% of the transplants could survive under pathological environment of the host spinal cord. They not only grew and differentiated continuously but also connected tightly with the host tissue. It is suggested that the defect tissue of injured adult spinal cord may at least be repaired with homotypic tissue by transplanting embryonic spinal cord cautiously with suitable age.