The change of serum insulin-like growth factor-Ⅰlevel in senile patients with type 2 diabetes mellitus after regular insulin therapy / 中华内分泌代谢杂志
Chinese Journal of Endocrinology and Metabolism
;
(12)2001.
Artigo
em Chinês
| WPRIM
| ID: wpr-536192
ABSTRACT
Objective To investigate the change of serum insulin like growth factor Ⅰ (IGF Ⅰ) level in newly diagnosed senile patients with type 2 diabetes mellitus (DM) before and after regular insulin (RI) therapy. Methods Body mass index, blood pressure (BP), 24 hour urinary microalbumin (24hUAlb), fasting blood glucose (FBG), 2 hour postprandial blood glucose (P2hBG), serum insulin (Ins) and C peptide (C P), HbA 1c and IGF Ⅰ were measured in 60 senile type 2 DM patients newly diagnosed by oral glucose tolerance test (OGTT) and 40 healthy senile subject (controls); RI 8 U, 6 U, 6 U were injected to type 2 DM patients before three meals respectively. Two days later, above tests were repeated. Insulin resistance index (IR) was calculated. Results The serum IGF Ⅰ levels were (349.0?49.5)?g/L in control group, (231.8?64.4)?g/L and (294.2?46.2)?g/L in patient group before and after RI therapy, The IGF Ⅰ level was significantly lower before RI therapy than that of controls (P
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Endocrinology and Metabolism
Ano de publicação:
2001
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS