Joint Effects of Over Intake of Fluoride and Iodine-Deficiency on Thyroid Glands of Pregnant Mice and Their Offspring / 环境与健康杂志
Journal of Environment and Health
;
(12)1992.
Artigo
em Chinês
| WPRIM
| ID: wpr-537084
ABSTRACT
Objective To discuss the effects of high-fluoride intake and iodine-deficiency on thyroid glands of pregnant mice and their offspring. Methods 200 mg/ L sodium fluoride solution was supplied ad.lib. for the adult female Kunming mice before pregnancy and during pregnancy with iodine-sufficiency and iodine-deficiency. The morphological changes and functions of thyroid glands and the body weights of the pregnant mice and their offspring were observed and measured. Results Under the condition of iodine-sufficiency, significantly higher levels of blood T4 in pregnant mice exposed to high-dose fluoride and their offspring were observed compared with those of control group. Significantly heavier body weights were found in 18 d-pregnant mice and 7 d-old offspring compared with those of control group (P
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Journal of Environment and Health
Ano de publicação:
1992
Tipo de documento:
Artigo
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