Nuclear Factor-?B and Colon Cancer / 中国普外基础与临床杂志
Chinese Journal of Bases and Clinics in General Surgery
;
(12)2003.
Artigo
em Chinês
| WPRIM
| ID: wpr-537774
ABSTRACT
Objective To explore the relationship between nuclear factor ?B (NF ?B) and the occurrence, metastasis, and treatment of colon cancer. Methods The literature on the structure and the property of molecular biology of NF ?B, the relationship between NF ?B and apopotosis, malignant tumor and colon cancer were reviewed.Results NF ?B had action of antiapopotosis. The occurrence of malignant tumor had close relation with the oncogene by NF ?B, the metastasis of malignant tumor was that cell of cancer escaped the killing and supervising of immunity by NF ?B. NF ?B affected the occurrence and metastasis of colon cancer by regulating c myc, Cox2, ICAM 1.Conclusion NF ?B has important action in the occurrence and metastasis of colon cancer. It will become a new target of treatment.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Bases and Clinics in General Surgery
Ano de publicação:
2003
Tipo de documento:
Artigo
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