Expression of KAI1 protein and its clinicopathological significance in breast cancer / 中国癌症杂志
China Oncology
; (12)2001.
Article
em Zh
| WPRIM
| ID: wpr-539465
Biblioteca responsável:
WPRO
ABSTRACT
Purpose: To investigate the expression of KAI1 protein and its clinicopathological significance in breast cancer. Methods: Immunohistochemical staining ( S-P method) was used to detect the expression of KAI1 protein in specimens from 107 breast cancer and 30 adjacent normal breast tissues. Results: KAI1 protein positive rate in breast cancer tissues is significantly lower than that of adjacent nomal breast( P 0. 05). Conclusions: These data suggest that in advanced breast cancer, KAI1 is down-regulated and decrease in KAI1 ecpression plays an important role in the malignant progression of breast cancer. Therefore, detection of KAI1 protein might be a potentially valuable indicator for staging human breast cancer and predicting prognosis.
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Índice:
WPRIM
Idioma:
Zh
Revista:
China Oncology
Ano de publicação:
2001
Tipo de documento:
Article