Changes and significance of cytokine signaling suppressor mRNA in burn rats with Staphylococcus aureus sepsis / 中华创伤杂志
Chinese Journal of Trauma
;
(12)2003.
Artigo
em Chinês
| WPRIM
| ID: wpr-540484
ABSTRACT
Objective To observe the expression law of cytokine signaling suppressors (SOCSs) mRNA in burn rats with Staphylococcus aureus sepsis and investigate their potential role in the pathogenesis of postburn sepsis. Methods Wistar rats were inflicted with 20% TBSA Ⅲ? scald, followed by Staphylococcus aureus challenge. Then, the expressions of SOCS1, SOCS2 and SOCS3 mRNA and interferon-? (IFN-?) levels in the liver and lungs were determined. Results With Staphylococcus aureus challenge after burn, IFN-? levels in the liver and lungs were significantly elevated and reached peak at the 0.5th and 6th hours, respectively (P
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Trauma
Ano de publicação:
2003
Tipo de documento:
Artigo
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