Preparation of monoclonal antibody against human colorectal cancer and its application in tumor research / 中国免疫学杂志

ABSTRACT

Objective:To produce the mAb which specifically reacting with colorectal cancer confirmed by the tissue microarray technology.Methods:The mice were immunize with LOVO, and the mAb were screened by indirect cell ELISA and immunohistochemistry.Results:A McAb was obtained which can react to the colon cancer, but very little or not to normal tissue and other caner tissues.Conclusion:A McAb which can react to the colon cancer have been obtained,and the McAb can be useful on clinic for diagnosis and prognosis of colorectal cancer.