Diagnosis and treatment of bladder non-epithelial tumors (report of 25 cases) / 中华泌尿外科杂志

ABSTRACT

Objective To summarize the characteristics of images and clinical diagnosis of bladdernon-epithelial tumors,and to investigate the relationship between the therapeutic methods and prognosis of thedisease. Methods The clinical data of 25 patients (16 males and 9 females,aged between 2 -71 years)with bladder non-epithelial tumors treated in our hospital were retrospectively analyzed.The clinical manifes-tations included hematuria (6 patients),lower abdominal lump (2),frequent urination (14),dysuria (2)and fainting during voiding (1).Ultrasound and CT examinations suggested space-occupying lesions in thebladder in 22 patients and pelvic tumor involving the bladder wall in the other3 patients.Cystoscopy was per-formed in all patients and 17 patients got biopsy. Results Simple tumor resection or partial cystectomywas carried out in 15 patients with benign tumors;the rest 10 patients with malignant tumors underwent par-tial or radical cystectomy. Adjuvant radiotherapy and chemotherapy were performed in malignant tumor pa-tients.Follow-up time was 3 months to 11years.No recurrence was found in benign tumor patients.Nine pa-tients with malignant tumors died in 3 years after operation (mean survival time of 16 months).A patientwith bladder malignant lymphoma survived for6 years.Three recurrences occurred in another bladder leiomy-osarcoma patient who had tumor resection. Conclusions Bladder non-epithelial tumors are relatively rarein clinical.The pathological types of the tumors are complicated,most of them are malignant and the progno-sis is relatively poor.The clinical perception of these tumors is inadequate and misdiagnosis rate is high.Deep-site biopsy under cystoscope can improve the diagnostic rate.Partial or radical cystectomy is the maintherapy for these tumors,and adjuvant radiotherapy and chemotherapy can be used according to the pathologi-cal features, but the effects are uncertain and the prognosis is quite different.