Effects of different frash gas flow of oxygen ventilation on recovery experience during Enflurane general anesthesia / 中国现代普通外科进展

ABSTRACT

Objective: To investigate effects of different frash gas flow of oxygen ventila-tion on emergence time and delirium undergoing Enflurane general anesthesia. Methods: Forty- eight patients, ASA Ⅰ- Ⅱ, aged 33- 68yr, mean 50.5yr, underwent elective abdominal op-eration were randomly divided into three groups according to the different frash gas flow at the end of operation GroupⅠ, the flow of oxygen maintained at 2 L/min, GroupⅡ 4 L/min, GroupⅢ 10 L/min. Anesthesia was induced with intravenous midazolam 0.08- 0.1mg/kg, etomidate 15- 20mg,fentanyl 3- 4 ?g/kg, pipecuronium 0.08- 0.1mg/kg and maintained with Enflurane(1.5- 2.0vol%), supplemented with intermittent iv pipecuronium and fentanyl. The concentration of Enflurane was monitored continuous which involved Fi, Fa and Fao, originated from inspiration, expiration and the moment expiration when stopped inhalation. Accounted Fao and after this detailed every one minute Fa until the patients recovery and calculated Fa/Fao ratio. Emergence time was recorded. Mini- Mental State Examination (MMSE) was performed before anesthesia and after surgery. Results: Fa/Fao ratio in GroupⅠ was significantly defferent from GroupⅡ and Ⅲ. MMSE scores in GroupⅠwere higher compare with GroupⅡand Ⅲ after surgery. Emergence time was no signif-icantly difference among three groups. Conclusion: The frash gas low flow of oxygen ventila-tion might reduce the incidence of delirium,but does not influnce the time of emergence from general anesthesia.