Change of TNF-?and VEGF on glucocorticoid-induced avascular necrosis of femoral head in rabbits / 中国矫形外科杂志
Orthopedic Journal of China
;
(24)2006.
Artigo
em Chinês
| WPRIM
| ID: wpr-543273
ABSTRACT
[Objective]To establish animal model of avascular necrosis of the femoral head in rabbits induced by glucocorti-coid, to further investigate the pathogenesis of glucocorticoid-induced osteonecrosis.[Method]Twenty NewZealand white rabbitswere used and randomly divided into two groups.Group A was injected with horse serum and prednisone. Group B was used asthe control.The concentration of TNF-?was measured by ELISA in rabbits serum of group A and group B.Femoral head speci-mens were studied by histopathologic examination and the expression of VEGF by immunohistochemical examination.[Result]The concentration of TNF-?in rabbits serum of group A was higher than that of group B(P
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Estudo prognóstico
Idioma:
Chinês
Revista:
Orthopedic Journal of China
Ano de publicação:
2006
Tipo de documento:
Artigo
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