Relationship of Magnetic Resonance Diffusion-Weighted Imaging to Histology in Chronic Viral Hepatitis / 中国普外基础与临床杂志
Article
em Zh
| WPRIM
| ID: wpr-543546
Biblioteca responsável:
WPRO
ABSTRACT
Objective To investigate the relationship of magnetic resonance diffusion-weighted imaging (DWI) to histology in the patients of chronic viral hepatitis. Methods Thirty-five patients of chronic viral hepatitis who received liver biopsy and 10 healthy volunteers were included in this study. All of them underwent DWI on a 3.0T MRI device. Apparent diffusion coefficient (ADC) of the liver were measured respectively when b value were set as 100, 400, 600 and 800 s/mm~2. Biopsy specimens were scored for fibrosis and necroinflammation according to the Knodell histology activity index (HAI). Results When b value was set as 800 s/mm~2, statistical difference was showed between the fibrosis group and the non-fibrosis group, statistical difference was also shown among the different degrees of necroinflammation and fibrosis. Conclusion DWI is a valuable method for grading and staging of chronic viral hepatitis.
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Índice:
WPRIM
Idioma:
Zh
Revista:
Chinese Journal of Bases and Clinics in General Surgery
Ano de publicação:
2003
Tipo de documento:
Article