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The effect of lipoxygenase inhibitor (NDGA) on the expression of VEGF and CD44V6 in breast cancer MCF-7 cells / 中国现代普通外科进展
Chinese Journal of Current Advances in General Surgery ; (4)2004.
Artigo em Chinês | WPRIM | ID: wpr-544054
ABSTRACT

Objective:

To explore the effects of VEGF and CD44V6 on breast cancer MCF-7 cells by NDGA.

Methods:

MCF-7 cells in the logarithmic growth state were selected and measured.There were four cell groups(concentration0,1,10,100?mol/L)in the experiment.After 48h treatment of NDGA,the expression of VEGFmRNA was measured by RT-PCR and the expression of CD44V6 was examined by flow cytometry.

Results:

After treatment of NDGA,the expressions of VEGFmRNA and CD44V6 in NDGA groups were significantly lower than that of the control group(F=2996.13,P

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: Chinese Journal of Current Advances in General Surgery Ano de publicação: 2004 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: Chinese Journal of Current Advances in General Surgery Ano de publicação: 2004 Tipo de documento: Artigo