Effect of Ginsenosides on Learning,Memory and Activity of Rats During Sleep Deprivation / 中国临床心理学杂志

ABSTRACT

Objective: To explore the effects of ginsenosides(GS) on learning,memory and activity of rats during sleep deprivation(SD).Methods: SD was induced in Sprague-Dawlay rats by employing "flower pot" technique.The rats were randomly divided into five groups according to the time of SD(0-96h),and every group was also divided into two subgroups experimental group(E) and control group(C).Forced feeding of GS to the experimental rats for 5 d before the rats were deprived of sleep.Before and after SD immediately,the behaviors of rats were studied in "Y" maze test,step-down test and open-field test.Results: ①"Y" maze test As compared with those of the controls,the accuracy of response of experimental groups increased significantly in 24h,48h,72h and 96h(P