The function of caveolins in neoplasia and its progressing / 中国癌症杂志
China Oncology
;
(12)2001.
Artigo
em Chinês
| WPRIM
| ID: wpr-544933
ABSTRACT
Caveolin,a membrane protein of 21-24 k,is the main structural component of caveolae,it plays quite a diverse functional role in maintaining vital activities of cells like endocytosis,cholesterol transport,cell membrane composition,and transduction of transmembrane signal to some virus involved in the processes of virus infection.Caveolin-1 also is a key regulator of multiple steps of oncogenesis and tumor development.Caveolin-1 can also serve as a negative regulator in proliferation,apoptosis,invasion and metastasis in varieties of cancer cells.There are some conflicting roles in different tumors,this review summarized the recent advances in the function of caveolin in cancers.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
China Oncology
Ano de publicação:
2001
Tipo de documento:
Artigo
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