Expression of p57~(kip2) and cyclin D1 in human glioma and its clinical significance / 西安交通大学学报(医学版)

ABSTRACT

Objective To investigate the expression of p57kip2 and cyclin D1 in human brain glioma and its clinical significance.Methods The expression of p57kip2 and cyclin D1 was detected by SP immunohistochemical technique in brain glioma(n=55) and normal brain tissues(n=10).Results Positive rate of p57kip2 protein in the 55 cases of brain glioma was 38.2%(21/55),significantly lower than that in normal brain tissues(80%,P