Efficacy of deproteinised cancellous bone combined with BMP and fibrin in healing of rabbit segmental radial defect / 中国矫形外科杂志
Orthopedic Journal of China
; (24)2006.
Article
em Zh
| WPRIM
| ID: wpr-546480
Biblioteca responsável:
WPRO
ABSTRACT
[Objective]To repair segmental bone defect with the composite of deproteinised cancellous bone,bone morphogenetic protein(BMP) and fibrin.[Method] Bone defects were created in 36 New Zealand rabbits on the bilateral radii and treated with three kinds of implantations:A,composite of deproteinised cancellous bone,BMP and fibrin;B,of deproteinised cancellous bone;C,blank control.The defects were observed by entgenography,optical microscopy,and electron-microscopy at 2,4,8,12,16 weeks.[Result] The defects treated with A implantation regenerated much more new bone and bridged earlier than the defects treated with B implantation and got completely repaired 16 weeks after operation.The defects with B and C implantation couldn't get osseous tissue healing.[Conclusion]The composite of deproteinised cancellous bone,bone morphogenetic protein(BMP) and fibrin can be effectively used to repair segmental bone defect.
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1
Índice:
WPRIM
Idioma:
Zh
Revista:
Orthopedic Journal of China
Ano de publicação:
2006
Tipo de documento:
Article