The Research on MR Perfusion Imaging of Normal Pancreas and Pancreatic Cancer / 实用放射学杂志

ABSTRACT

Objective To explore the characteristics of MR perfusion imaging in normal pancreas and pancreatic cancer.Methods 20 cases of normal pancreas(without pancreatic diseases)and 20 cases with pancreatic cancer,underwent MR perfusion imaging using PHILIPS 1.5T unit with T1WI 3DFFE.12?4 collimation, 4 mm slice thickness ,20ml Gadopentetic Acid Dimeglumine 0.5mmol/ml Magnevist were used, the flow rate was 3.5 ml/s with a power injection,5 seconds delay,and data acquisition lasted for 90 seconds.These data were processed on a View Forum workstation using MR Brest Imaging(in Qualitity Analysis)software package ,and the mean maximum relative enhancement,wash in rate, wash out rate, time to peak, time of arrival and area under the curve were measured and statistically analyzed.Results The data of perfusion imaging in normal pancreas and carcinous pancreas were as followed respectivelymaximum relative enhancement 95.69% and 50.74%,wash in rate 19.511/s and 4.471/s,wash out rate 26.051/s and 19.151/s,time to peak 31.33 s and 106.84 s,time of arrival 20.53 s and 64.70 s,area under the curve 15924.56 ml/(min? kg) and 5542.85 ml/(min ?kg).t-test showed that the difference of the perfusion data between normal pancreas and carcinous pancreas were significant(P